Sulfo DBCO-TFP Ester

货号
规格
价格
品牌
货期
1400-10
10 mg
2300.0
ClickChemistryTools
现询
1400-25
25 mg
3900.0
ClickChemistryTools
现询
1400-100
100 mg
9900.0
ClickChemistryTools
现询
1400-500
500 mg
25900.0
ClickChemistryTools
现询

Sulfo DBCO-TFP Ester is a water-soluble, amine-reactive labeling reagent that enables simple and efficient incorporation of Sulfo DBCO moiety onto amine-containing molecules. The hydrophilic, sulfonated spacer arm greatly improves water solubility of DBCO derivatized molecules, in many cases making them completely soluble in aqueous media. A short spacer arm adds minimal mass to modified molecules.


2,3,5,6-tetrafluorophenyl (TFP) esters is another type of carboxylic acid derivative that react with primary amines forming covalent amide bond. The amine linkage bond is identical to one formed by the reaction between primary amines and NHS esters or sulfo-NHS esters. However, in most cases, TFP ester displays much better stability toward hydrolysis in aqueous media resulting in more efficiency and better reproducible labeling of biopolymers.


DBCO reagents are the most commonly used substrates for copper-free click chemistry reactions. DBCO compounds react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage.


分子量
604.53
分子式
C28H20F2N2O7S
CAS
2268816-76-6
溶(解)度
>95% (HPLC)
纯度
DMSO, DMF, DCM, THF, Chloroform, Water
外观
White to slightly grey amorphous solid
储存环境
-20°C. Desiccate
运输条件
Ambient temperature

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