6-Azidohexanoic Acid

货号
规格
价格
品牌
货期
1250-1G
1 g
3580.0
ClickChemistryTools
现询
1250-5G
5 g
5900.0
ClickChemistryTools
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1250-25G
25 g
19580.0
ClickChemistryTools
现询

6-Azidohexanoic acid is a six carbon saturated fatty acid with an ω-terminal azide group. This building block that can be reacted with primary amine groups in the presence activators (e.g. EDC, or DCC) forming a stable amide bond. The terminal azide group allows conjugation with compounds containing alkyne groups through a copper(I)-catalyzed cycloaddition reaction, also known as click chemistry. 6-Azidohexanoic acid is commonly used as a linker that is first acylated to one compound to create a derivative that can then be joined to another compound using click chemistry.

分子量
157.17
分子式
C6H11N3O2
CAS
79598-53-1
溶(解)度
DMSO, DMF, DCM, THF, Chloroform
纯度
>95% (HPLC)
外观
Colorless to slightly yellow oil
储存环境
-20°C. Desiccate
运输条件
Ambient temperature

1. Esser-Kahn, A. P., et al. (2020). Pathogen-like Nanoassemblies of Covalently Linked TLR Agonists Enhance CD8 and NK Cell-Mediated Antitumor Immunity. ACS Cent. Sci., 10, 1021. [ACS Publications]

2. Manna, S., et al. (2018). Immunomodulation of the NLRP3 Inflammasome through Structure-Based Activator Design and Functional Regulation via Lysosomal Rupture. ACS Cent. Sci., 4(8), 982-95. [PubMed]


                

CoA Lot 2301                          

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